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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse cortex, claustrum, thalamus, striatum (Cre lines)", "claim_text": "Full single-neuron reconstructions of 1,741 mouse neurons across cortex, claustrum, thalamus and striatum identified 11 major projection-neuron types with distinct morphological features and matched transcriptomic identities, with extensive projectional diversity within each major type.", "raw_fields": { "n": 1741, "doi": "10.1038/s41586-021-03941-1", "claim": "Full single-neuron reconstructions of 1,741 mouse neurons across cortex, claustrum, thalamus and striatum identified 11 major projection-neuron types with distinct morphological features and matched transcriptomic identities, with extensive projectional diversity within each major type.", "cite_key": "Peng2021", "evidence": "Sparse labelling, whole-brain imaging, single-neuron reconstruction, registration and transcriptomic matching across mouse brain regions.", "effect_size": "1,741 reconstructed neurons; 11 major projection types", "text_access": "abstract_only", "study_system": "mouse cortex, claustrum, thalamus, striatum (Cre lines)", "argument_role": "supporting", "replication_status": "independently_replicated", "claim_source_sentence": "We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1038/s41586-021-03970-w", "10.34133/research.0470" ], "effect_size_source_sentence": "We identified 11 major projection neuron types with distinct morphological features and corresponding transcriptomic identities." }, "section_id": "section_07", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json", "effect_size": "1,741 reconstructed neurons; 11 major projection types", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-aa79acad2563" ], "source_span": "We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice.", "study_system": "mouse cortex, claustrum, thalamus, striatum (Cre lines)", "evidence_refs": [ { "ref": "paper:paper-aa79acad2563" } ], "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Sparse labelling, whole-brain imaging, single-neuron reconstruction, registration and transcriptomic matching across mouse brain regions.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "independently_replicated", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }