Details

scope
mouse cortex, claustrum, thalamus, striatum (Cre lines)
section_id
section_07
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
effect_size
1,741 reconstructed neurons; 11 major projection types
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
source_span
We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice.
study_system
mouse cortex, claustrum, thalamus, striatum (Cre lines)
section_title
7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity
evidence_summary
Sparse labelling, whole-brain imaging, single-neuron reconstruction, registration and transcriptomic matching across mouse brain regions.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
independently_replicated
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-07-celltype-motifs
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Full single-neuron reconstructions of 1,741 mouse neurons across cortex, claustrum, thalamus and striatum identified 11 major projection-neuron types with distinct morphological features and matched transcriptomic identities, with extensive projectional diversity within each major type.
raw_fields
{
  "n": 1741,
  "doi": "10.1038/s41586-021-03941-1",
  "claim": "Full single-neuron reconstructions of 1,741 mouse neurons across cortex, claustrum, thalamus and striatum identified 11 major projection-neuron types with distinct morphological features and matched transcriptomic identities, with extensive projectional diversity within each major type.",
  "cite_key": "Peng2021",
  "evidence": "Sparse labelling, whole-brain imaging, single-neuron reconstruction, registration and transcriptomic matching across mouse brain regions.",
  "effect_size": "1,741 reconstructed neurons; 11 major projection types",
  "text_access": "abstract_only",
  "study_system": "mouse cortex, claustrum, thalamus, striatum (Cre lines)",
  "argument_role": "supporting",
  "replication_status": "independently_replicated",
  "claim_source_sentence": "We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [
    "10.1038/s41586-021-03970-w",
    "10.34133/research.0470"
  ],
  "effect_size_source_sentence": "We identified 11 major projection neuron types with distinct morphological features and corresponding transcriptomic identities."
}
source_refs
[
  "paper:paper-aa79acad2563"
]
evidence_refs
[
  {
    "ref": "paper:paper-aa79acad2563"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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