Details
- scope
- Cervical dystonia patients with bilateral chronic GPi-DBS
- claim_text
- In cervical dystonia patients with chronic GPi-DBS, the best acute clinical improvement requires high frequency (≥60 Hz) and high voltage; 130 Hz produces the best response, while pulse-width has little effect.
- section_id
- section_14
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
- effect_size
- TWSTRS severity reduced 56.7% at best settings
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-14
- source_kind
- review_finding
- source_path
- evidence/section_14_evidence_package.json
- source_span
- Improvement was significantly associated with high frequency (> or = 60 Hz) and high voltage. Stimulation at 130 Hz showed the best clinical improvement.
- study_system
- Cervical dystonia patients with bilateral chronic GPi-DBS
- section_title
- Loop Dysfunction in Neurological and Psychiatric Disease
- evidence_summary
- Acute parameter randomized double-blind testing of 10 GPi-DBS settings in 8 cervical dystonia patients with mean 28.6-month chronic stimulation.
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-14
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 8, "doi": "10.1111/j.1468-1331.2008.02520.x", "claim": "In cervical dystonia patients with chronic GPi-DBS, the best acute clinical improvement requires high frequency (≥60 Hz) and high voltage; 130 Hz produces the best response, while pulse-width has little effect.", "cite_key": "Moro2009", "evidence": "Acute parameter randomized double-blind testing of 10 GPi-DBS settings in 8 cervical dystonia patients with mean 28.6-month chronic stimulation.", "effect_size": "TWSTRS severity reduced 56.7% at best settings", "text_access": "abstract_only", "study_system": "Cervical dystonia patients with bilateral chronic GPi-DBS", "source_cluster_id": "cluster_13", "replication_status": "independently_replicated", "claim_source_sentence": "Improvement was significantly associated with high frequency (> or = 60 Hz) and high voltage. Stimulation at 130 Hz showed the best clinical improvement.", "replication_evidence_dois": [ "10.3389/fneur.2026.1735832", "10.3390/toxins18020079" ], "effect_size_source_sentence": "The TWSTRS severity scores were reduced by 56.7% with stimulation at the best settings." }- source_refs
[ "paper:paper-e11f4f06356b" ]
- evidence_refs
[ { "ref": "paper:paper-e11f4f06356b" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }