Version history

{
  "scope": "Cervical dystonia patients with bilateral chronic GPi-DBS",
  "claim_text": "In cervical dystonia patients with chronic GPi-DBS, the best acute clinical improvement requires high frequency (≥60 Hz) and high voltage; 130 Hz produces the best response, while pulse-width has little effect.",
  "raw_fields": {
    "n": 8,
    "doi": "10.1111/j.1468-1331.2008.02520.x",
    "claim": "In cervical dystonia patients with chronic GPi-DBS, the best acute clinical improvement requires high frequency (≥60 Hz) and high voltage; 130 Hz produces the best response, while pulse-width has little effect.",
    "cite_key": "Moro2009",
    "evidence": "Acute parameter randomized double-blind testing of 10 GPi-DBS settings in 8 cervical dystonia patients with mean 28.6-month chronic stimulation.",
    "effect_size": "TWSTRS severity reduced 56.7% at best settings",
    "text_access": "abstract_only",
    "study_system": "Cervical dystonia patients with bilateral chronic GPi-DBS",
    "source_cluster_id": "cluster_13",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Improvement was significantly associated with high frequency (> or = 60 Hz) and high voltage. Stimulation at 130 Hz showed the best clinical improvement.",
    "replication_evidence_dois": [
      "10.3389/fneur.2026.1735832",
      "10.3390/toxins18020079"
    ],
    "effect_size_source_sentence": "The TWSTRS severity scores were reduced by 56.7% with stimulation at the best settings."
  },
  "section_id": "section_14",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "effect_size": "TWSTRS severity reduced 56.7% at best settings",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-14",
  "source_kind": "review_finding",
  "source_path": "evidence/section_14_evidence_package.json",
  "source_refs": [
    "paper:paper-e11f4f06356b"
  ],
  "source_span": "Improvement was significantly associated with high frequency (> or = 60 Hz) and high voltage. Stimulation at 130 Hz showed the best clinical improvement.",
  "study_system": "Cervical dystonia patients with bilateral chronic GPi-DBS",
  "evidence_refs": [
    {
      "ref": "paper:paper-e11f4f06356b"
    }
  ],
  "section_title": "Loop Dysfunction in Neurological and Psychiatric Disease",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Acute parameter randomized double-blind testing of 10 GPi-DBS settings in 8 cervical dystonia patients with mean 28.6-month chronic stimulation.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-14",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}