Version history

{
  "scope": "mouse hippocampus, transgenic and inducible MGE/CGE reporter mice",
  "claim_text": "Hippocampal interneurons are produced in two distinct neurogenic waves — MGE between E9–E12 and CGE between E12–E16 — and invade the hippocampus by E14; in the mature hippocampus, CGE-derived interneurons preferentially populate strata lacunosum moleculare and deep radiatum (CCK+, calretinin+, VIP+, reelin+ subtypes), while MGE-derived populations dominate strata pyramidale and oriens (parvalbumin+, somatostatin+).",
  "raw_fields": {
    "n": null,
    "doi": "10.1523/jneurosci.0323-11.2011",
    "claim": "Hippocampal interneurons are produced in two distinct neurogenic waves — MGE between E9–E12 and CGE between E12–E16 — and invade the hippocampus by E14; in the mature hippocampus, CGE-derived interneurons preferentially populate strata lacunosum moleculare and deep radiatum (CCK+, calretinin+, VIP+, reelin+ subtypes), while MGE-derived populations dominate strata pyramidale and oriens (parvalbumin+, somatostatin+).",
    "title": null,
    "cite_key": "Tricoire2011",
    "evidence": "Abstract: combined molecular, anatomical, and electrophysiological characterization in MGE- and CGE-specific transgenic and inducible mouse lines.",
    "effect_size": "MGE wave E9–E12; CGE wave E12–E16; invasion by E14",
    "figure_data": [
      {
        "type": "developmental_timing",
        "unit": "embryonic day (mouse)",
        "metric": "MGE neurogenic wave",
        "source": "Abstract",
        "value_max": "E12",
        "value_min": "E9"
      },
      {
        "type": "developmental_timing",
        "unit": "embryonic day (mouse)",
        "metric": "CGE neurogenic wave",
        "source": "Abstract",
        "value_max": "E16",
        "value_min": "E12"
      }
    ],
    "text_access": "abstract_only",
    "study_system": "mouse hippocampus, transgenic and inducible MGE/CGE reporter mice",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "replicated",
    "_source_cluster_index": 13,
    "claim_source_sentence": "We found that hippocampal interneurons are produced in two neurogenic waves between E9-E12 and E12-E16 from MGE and CGE, respectively, and invade the hippocampus by E14.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.5123-09.2010"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": "MGE wave E9–E12; CGE wave E12–E16; invasion by E14",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:paper-6cdec9b9ae1d"
  ],
  "source_span": "We found that hippocampal interneurons are produced in two neurogenic waves between E9-E12 and E12-E16 from MGE and CGE, respectively, and invade the hippocampus by E14.",
  "study_system": "mouse hippocampus, transgenic and inducible MGE/CGE reporter mice",
  "evidence_refs": [
    {
      "ref": "paper:paper-6cdec9b9ae1d"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Abstract: combined molecular, anatomical, and electrophysiological characterization in MGE- and CGE-specific transgenic and inducible mouse lines.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}