Version history

{
  "scope": "mouse; visual cortex; two-photon imaging, whole-cell patch, in vivo; Nature",
  "claim_text": "Here we directly relate patterns of excitatory synaptic connectivity to visual response properties of neighbouring layer 2/3 pyramidal neurons in mouse visual cortex at different postnatal age…",
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    "evidence": "Sensory processing occurs in neocortical microcircuits in which synaptic connectivity is highly structured and excitatory neurons form subnetworks that process related sensory information. However, the developmental mechanisms underlying the formation of functionally organized connectivity in cortical microcircuits remain unknown. Here we directly relate patterns of excitatory synaptic connectivity to visual response properties of neighbouring layer 2/3 pyramidal neurons in mouse visual c...",
    "effect_size": "We next tested for developmental changes in recurrent connectivity between neurons not reliably responsive to visual stimuli, which were encountered at similar proportions at both age groups (fraction of non-significantly responsive neurons to repeated presentations of the natural movie: P13 – 15, 39%, 4133/10509 neurons; P22 – 26, 44%, 4691/10662).",
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    "effect_size_source_sentence": "We next tested for developmental changes in recurrent connectivity between neurons not reliably responsive to visual stimuli, which were encountered at similar proportions at both age groups (fraction of non-significantly responsive neurons to repeated presentations of the natural movie: P13 – 15, 39%, 4133/10509 neurons; P22 – 26, 44%, 4691/10662)."
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  "effect_size": "We next tested for developmental changes in recurrent connectivity between neurons not reliably responsive to visual stimuli, which were encountered at similar proportions at both age groups (fraction of non-significantly responsive neurons to repeated presentations of the natural movie: P13 – 15, 39%, 4133/10509 neurons; P22 – 26, 44%, 4691/10662).",
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  "study_system": "mouse; visual cortex; two-photon imaging, whole-cell patch, in vivo; Nature",
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  "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
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