Version history

{
  "scope": "mouse barrel cortex in vivo, optogenetics",
  "claim_text": "Light-driven activation of fast-spiking interneurons at varied frequencies selectively amplifies gamma oscillations (8-200 Hz range tested), while pyramidal neuron activation amplifies only lower frequency oscillations - a cell-type-specific double dissociation",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nature08002",
    "claim": "Light-driven activation of fast-spiking interneurons at varied frequencies selectively amplifies gamma oscillations (8-200 Hz range tested), while pyramidal neuron activation amplifies only lower frequency oscillations - a cell-type-specific double dissociation",
    "evidence": "Light-driven activation of fast-spiking interneurons at varied frequencies selectively amplifies gamma oscillations (8-200 Hz range tested), while pyramidal neuron activation amplifies only lower frequency oscillations - a cell-type-specific double dissociation",
    "effect_size": "Sensory input timing relative to gamma cycle determined amplitude and precision of evoked responses",
    "text_access": "fulltext",
    "study_system": "mouse barrel cortex in vivo, optogenetics",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Here we show that light-driven activation of fast-spiking interneurons at varied frequencies (8-200 Hz) selectively amplifies gamma oscillations. In contrast, pyramidal neuron activation amplifies only lower frequency oscillations, a cell-type-specific double dissociation.",
    "replication_evidence_dois": [
      "10.1038/nature07991",
      "10.1016/j.neuron.2017.11.033"
    ],
    "effect_size_source_sentence": "We found that the timing of a sensory input relative to a gamma cycle determined the amplitude and precision of evoked responses."
  },
  "section_id": "section_10_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json",
  "effect_size": "Sensory input timing relative to gamma cycle determined amplitude and precision of evoked responses",
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  "source_kind": "review_finding",
  "source_path": "evidence/section_10_evidence_package.json",
  "source_refs": [
    "paper:3767f6c5-663b-42ad-bf68-d37f6f00b49d"
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  "source_span": "Here we show that light-driven activation of fast-spiking interneurons at varied frequencies (8-200 Hz) selectively amplifies gamma oscillations. In contrast, pyramidal neuron activation amplifies only lower frequency oscillations, a cell-type-specific double dissociation.",
  "study_system": "mouse barrel cortex in vivo, optogenetics",
  "evidence_refs": [
    {
      "ref": "paper:3767f6c5-663b-42ad-bf68-d37f6f00b49d"
    }
  ],
  "section_title": "Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony",
  "source_policy": {
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    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Light-driven activation of fast-spiking interneurons at varied frequencies selectively amplifies gamma oscillations (8-200 Hz range tested), while pyramidal neuron activation amplifies only lower frequency oscillations - a cell-type-specific double dissociation",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-10",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}