Version history

{
  "scope": "mouse primary whisker somatosensory cortex (barrel cortex) L2/3 excitatory neurons",
  "claim_text": "Single-cell electroporation followed by two-photon serial-section tomography of individual mouse barrel-cortex L2/3 excitatory neurons reveals that each neuron has an extensive local intra-barrel axon plus brain-wide axonal arborizations innervating multiple long-range targets (S2; primary somatosensory cortex of upper limb, trunk, lower limb; M1; M2; visual and auditory cortices; dorsolateral striatum; fiber bundles), demonstrating substantial single-cell heterogeneity of long-range targeting within the L2/3 IT class.",
  "raw_fields": {
    "n": 0,
    "doi": "10.3389/fnana.2021.791015",
    "claim": "Single-cell electroporation followed by two-photon serial-section tomography of individual mouse barrel-cortex L2/3 excitatory neurons reveals that each neuron has an extensive local intra-barrel axon plus brain-wide axonal arborizations innervating multiple long-range targets (S2; primary somatosensory cortex of upper limb, trunk, lower limb; M1; M2; visual and auditory cortices; dorsolateral striatum; fiber bundles), demonstrating substantial single-cell heterogeneity of long-range targeting within the L2/3 IT class.",
    "cite_key": "Liu2022b",
    "evidence": "Single-cell electroporation labeling, two-photon serial-section tomography of single barrel-cortex L2/3 pyramidal neurons and registration to a digital brain atlas in mouse.",
    "effect_size": "qualitative — diverse single-cell long-range target spectra within L2/3 IT class",
    "text_access": "fulltext",
    "study_system": "mouse primary whisker somatosensory cortex (barrel cortex) L2/3 excitatory neurons",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Each neuron had an extensive local axon within the barrel cortex. In addition, individual neurons innervated subsets of secondary somatosensory cortex; primary somatosensory cortex for upper limb, trunk, and lower limb; primary and secondary motor cortex; visual and auditory cortical regions; dorsolateral striatum; and various fiber bundles",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.3389/fnana.2018.00033"
    ],
    "effect_size_source_sentence": "individual neurons innervated subsets of secondary somatosensory cortex... primary and secondary motor cortex; visual and auditory cortical regions"
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — diverse single-cell long-range target spectra within L2/3 IT class",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-574c53257981"
  ],
  "source_span": "Each neuron had an extensive local axon within the barrel cortex. In addition, individual neurons innervated subsets of secondary somatosensory cortex; primary somatosensory cortex for upper limb, trunk, and lower limb; primary and secondary motor cortex; visual and auditory cortical regions; dorsolateral striatum; and various fiber bundles",
  "study_system": "mouse primary whisker somatosensory cortex (barrel cortex) L2/3 excitatory neurons",
  "evidence_refs": [
    {
      "ref": "paper:paper-574c53257981"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Single-cell electroporation labeling, two-photon serial-section tomography of single barrel-cortex L2/3 pyramidal neurons and registration to a digital brain atlas in mouse.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}