Version history

{
  "scope": "mouse PFC–visTRN–LGN (cross-modal divided-attention task)",
  "claim_text": "Cross-modal sensory selection in mice depends on PFC interactions with the visual thalamic reticular nucleus (visTRN), whose feedforward inhibition dynamically controls visual thalamic gain.",
  "raw_fields": {
    "n": 15,
    "doi": "10.1038/nature15398",
    "claim": "Cross-modal sensory selection in mice depends on PFC interactions with the visual thalamic reticular nucleus (visTRN), whose feedforward inhibition dynamically controls visual thalamic gain.",
    "cite_key": "Wimmer2015",
    "evidence": "Optogenetic perturbations of PFC and visTRN with electrophysiology and intracellular chloride photometry during a cross-modal divided-attention task in mice.",
    "effect_size": "Performance on two modalities balanced; n=15 mice; visTRN photoinhibition produces modality-specific behavioral changes",
    "text_access": "fulltext",
    "study_system": "mouse PFC–visTRN–LGN (cross-modal divided-attention task)",
    "source_cluster_id": "cluster_05",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Equivalent sensory thalamocortical manipulations showed that behaviour was causally dependent on PFC interactions with the sensory thalamus, not sensory cortex.",
    "replication_evidence_dois": [
      "10.1126/science.1223082",
      "10.1038/nature22073"
    ],
    "effect_size_source_sentence": "Performance on the two modalities was balanced (n = 15 mice, Fig."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "effect_size": "Performance on two modalities balanced; n=15 mice; visTRN photoinhibition produces modality-specific behavioral changes",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-06",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-2a53381ce8a2"
  ],
  "source_span": "Equivalent sensory thalamocortical manipulations showed that behaviour was causally dependent on PFC interactions with the sensory thalamus, not sensory cortex.",
  "study_system": "mouse PFC–visTRN–LGN (cross-modal divided-attention task)",
  "evidence_refs": [
    {
      "ref": "paper:paper-2a53381ce8a2"
    }
  ],
  "section_title": "Thalamic Feedback: Closing the Loop",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Optogenetic perturbations of PFC and visTRN with electrophysiology and intracellular chloride photometry during a cross-modal divided-attention task in mice.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-06",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}