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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse S1 barrel cortex L2 and L3 pyramidal cells", "claim_text": "In mouse barrel cortex, the L4→L3 intracortical projection is confined within a single column (~157 µm lateral spread), while the L5A→L2 and L2/3→L2 projections are significantly wider (235 and 276 µm) and invade neighboring columns.", "raw_fields": { "n": 0, "doi": "10.1371/journal.pbio.0040382", "claim": "In mouse barrel cortex, the L4→L3 intracortical projection is confined within a single column (~157 µm lateral spread), while the L5A→L2 and L2/3→L2 projections are significantly wider (235 and 276 µm) and invade neighboring columns.", "cite_key": "Bureau2006", "evidence": "LSPS-derived synaptic input maps to identified L2 and L3 neurons in barrel-cortex slices.", "effect_size": "L4→L3: 157±6 µm; L5A→L2: 235±9 µm; L2/3→L2: 276±11 µm (mean lateral distance from map center)", "text_access": "fulltext", "study_system": "mouse S1 barrel cortex L2 and L3 pyramidal cells", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG).", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG)." }, "section_id": "section_04", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json", "effect_size": "L4→L3: 157±6 µm; L5A→L2: 235±9 µm; L2/3→L2: 276±11 µm (mean lateral distance from map center)", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar", "source_kind": "review_finding", "source_path": "evidence/section_04_evidence_package.json", "source_refs": [ "paper:126d45d1-af34-4bb8-acea-67031f7d19a6" ], "source_span": "Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG).", "study_system": "mouse S1 barrel cortex L2 and L3 pyramidal cells", "evidence_refs": [ { "ref": "paper:126d45d1-af34-4bb8-acea-67031f7d19a6" } ], "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "LSPS-derived synaptic input maps to identified L2 and L3 neurons in barrel-cortex slices.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }