Details

scope
mouse S1 barrel cortex L2 and L3 pyramidal cells
claim_text
In mouse barrel cortex, the L4→L3 intracortical projection is confined within a single column (~157 µm lateral spread), while the L5A→L2 and L2/3→L2 projections are significantly wider (235 and 276 µm) and invade neighboring columns.
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
effect_size
L4→L3: 157±6 µm; L5A→L2: 235±9 µm; L2/3→L2: 276±11 µm (mean lateral distance from map center)
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-04-translaminar
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
study_system
mouse S1 barrel cortex L2 and L3 pyramidal cells
section_title
4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
evidence_summary
LSPS-derived synaptic input maps to identified L2 and L3 neurons in barrel-cortex slices.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-04-translaminar
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1371/journal.pbio.0040382",
  "claim": "In mouse barrel cortex, the L4→L3 intracortical projection is confined within a single column (~157 µm lateral spread), while the L5A→L2 and L2/3→L2 projections are significantly wider (235 and 276 µm) and invade neighboring columns.",
  "cite_key": "Bureau2006",
  "evidence": "LSPS-derived synaptic input maps to identified L2 and L3 neurons in barrel-cortex slices.",
  "effect_size": "L4→L3: 157±6 µm; L5A→L2: 235±9 µm; L2/3→L2: 276±11 µm (mean lateral distance from map center)",
  "text_access": "fulltext",
  "study_system": "mouse S1 barrel cortex L2 and L3 pyramidal cells",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG).",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG)."
}
source_refs
[
  "paper:126d45d1-af34-4bb8-acea-67031f7d19a6"
]
source_span
Although the L4→L3projection was largely contained within one column (mean lateral distance from the center of map, 157 ± 6 μm,20; see), the L5A→L2(235 ± 9 μm,16) and L2/3→L2(276 ± 11 μm,16) projections were significantly wider (< 0.001, Wilcoxon) and invaded neighboring columns (A,F, andG).
evidence_refs
[
  {
    "ref": "paper:126d45d1-af34-4bb8-acea-67031f7d19a6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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