Details

scope
mouse barrel cortex and medial PFC; rabies-virus trans-synaptic input tracing
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
effect_size
L3→L6 ascending–descending excitatory input identified; laminar matching of long-range cortico-cortical inputs.
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-04-translaminar
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
source_span
In barrel cortex, we found substantial inputs from layer 3 (L3) to L6, prevalent translaminar inhibitory inputs, and long-range inputs to L2/3 or L5/6 preferentially from L2/3 or L5/6 of input cortical areas, respectively.
study_system
mouse barrel cortex and medial PFC; rabies-virus trans-synaptic input tracing
section_title
4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
evidence_summary
Monosynaptic rabies virus tracing from pyramidal neurons in mouse barrel cortex and mPFC.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-04-translaminar
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Rabies-based trans-synaptic tracing in mouse barrel cortex reveals substantial intracolumnar inputs from L3 to L6 and laminar specificity in long-range cortico-cortical inputs (L2/3 sources preferentially target L2/3, L5/6 sources target L5/6).
raw_fields
{
  "n": 0,
  "doi": "10.1038/nn.4131",
  "claim": "Rabies-based trans-synaptic tracing in mouse barrel cortex reveals substantial intracolumnar inputs from L3 to L6 and laminar specificity in long-range cortico-cortical inputs (L2/3 sources preferentially target L2/3, L5/6 sources target L5/6).",
  "cite_key": "DeNardo2015",
  "evidence": "Monosynaptic rabies virus tracing from pyramidal neurons in mouse barrel cortex and mPFC.",
  "effect_size": "L3→L6 ascending–descending excitatory input identified; laminar matching of long-range cortico-cortical inputs.",
  "text_access": "abstract_only",
  "study_system": "mouse barrel cortex and medial PFC; rabies-virus trans-synaptic input tracing",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "In barrel cortex, we found substantial inputs from layer 3 (L3) to L6, prevalent translaminar inhibitory inputs, and long-range inputs to L2/3 or L5/6 preferentially from L2/3 or L5/6 of input cortical areas, respectively.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-a8137b5bec6c"
]
evidence_refs
[
  {
    "ref": "paper:paper-a8137b5bec6c"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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