PV and SOM interneurons tightly control both up-to-down and down-to-up cortical…

Details

scope: mouse cortex, anesthetized and awake, optogenetics
claim_text: PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away
section_id: section_10_evidence_package
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
effect_size: Local manipulation affected cortical populations millimeters away from modulated region
review_repo: ComputationalReviewPV
section_ref: wiki_page:computationalreviewpv-10
source_kind: review_finding
source_path: evidence/section_10_evidence_package.json
source_span: Two major classes of interneurons, the parvalbumin and the somatostatin positive cells, tightly control both up-to-down and down-to-up state transitions.
study_system: mouse cortex, anesthetized and awake, optogenetics
section_title: Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony
evidence_summary: PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away
review_bundle_ref: analysis_bundle:ab-e6261c8263e7
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-e6261c8263e7
source_artifact_ref: wiki_page:computationalreviewpv-10
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
commit_sha: df9fc7e8d455b084152c9d713558dae0013cef21
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewPV

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.7554/eLife.26177",
  "claim": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away",
  "evidence": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away",
  "effect_size": "Local manipulation affected cortical populations millimeters away from modulated region",
  "text_access": "fulltext",
  "study_system": "mouse cortex, anesthetized and awake, optogenetics",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Two major classes of interneurons, the parvalbumin and the somatostatin positive cells, tightly control both up-to-down and down-to-up state transitions.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Finally, local manipulation of small ensembles of interneurons affected cortical populations millimetres away from the modulated region."
}

source_refs

[
  "paper:paper-535954fddc2e"
]

evidence_refs

[
  {
    "ref": "paper:paper-535954fddc2e"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

PV and SOM interneurons tightly control both up-to-down and down-to-up cortical…

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