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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse cortex, anesthetized and awake, optogenetics", "claim_text": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away", "raw_fields": { "n": 0, "doi": "10.7554/eLife.26177", "claim": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away", "evidence": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away", "effect_size": "Local manipulation affected cortical populations millimeters away from modulated region", "text_access": "fulltext", "study_system": "mouse cortex, anesthetized and awake, optogenetics", "replication_status": "replication_unknown", "claim_source_sentence": "Two major classes of interneurons, the parvalbumin and the somatostatin positive cells, tightly control both up-to-down and down-to-up state transitions.", "replication_evidence_dois": [], "effect_size_source_sentence": "Finally, local manipulation of small ensembles of interneurons affected cortical populations millimetres away from the modulated region." }, "section_id": "section_10_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json", "effect_size": "Local manipulation affected cortical populations millimeters away from modulated region", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-10", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:paper-535954fddc2e" ], "source_span": "Two major classes of interneurons, the parvalbumin and the somatostatin positive cells, tightly control both up-to-down and down-to-up state transitions.", "study_system": "mouse cortex, anesthetized and awake, optogenetics", "evidence_refs": [ { "ref": "paper:paper-535954fddc2e" } ], "section_title": "Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "PV and SOM interneurons tightly control both up-to-down and down-to-up cortical state transitions, with interneuron-type specific control; local manipulation of small interneuron ensembles affects cortical populations millimeters away", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-10", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }