- claim_text
A 10-laboratory International Brain Laboratory replication study repeatedly targeted Neuropixels probes to the same brain locations (secondary visual areas, hippocampus, and thalamus) in mice performing a standardized decision-making task and developed RIGOR histological and electrophysiological quality-control criteria to enhance reproducibility.
- raw_fields
{
"n": 121,
"doi": "10.7554/elife.100840",
"claim": "A 10-laboratory International Brain Laboratory replication study repeatedly targeted Neuropixels probes to the same brain locations (secondary visual areas, hippocampus, and thalamus) in mice performing a standardized decision-making task and developed RIGOR histological and electrophysiological quality-control criteria to enhance reproducibility.",
"cite_key": "InternationalBrainLaboratory2025b",
"evidence": "Empirical assessment that even with standardized hardware and task, electrode targeting and limited statistical power drive cross-lab variability; explicit QC criteria offered as mitigation.",
"effect_size": "121 experimental replicates from 10 labs",
"text_access": "fulltext",
"study_system": "Mouse multi-lab Neuropixels reproducibility study; secondary visual areas / hippocampus / thalamus",
"argument_role": "supporting",
"replication_status": "single-study",
"claim_source_sentence": "This pipeline included stringent new histological and electrophysiological quality-control criteria (the ‘Recording Inclusion Guidelines for Optimizing Reproducibility’ [RIGOR]) that are applicable to datasets beyond our own.",
"source_provenance_status": "ok",
"replication_evidence_dois": [],
"effect_size_source_sentence": "Experimenters in 10 laboratories repeatedly targeted Neuropixels probes to the same location (spanning secondary visual areas, hippocampus, and thalamus) in mice making decisions; this generated a total of 121 experimental replicates, a unique dataset for evaluating reproducibility of electrophysiology experiments."
}- source_refs
[
"paper:805df180-8279-474b-b134-8b931e75d832"
]
- evidence_refs
[
{
"ref": "paper:805df180-8279-474b-b134-8b931e75d832"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}