Version history

{
  "scope": "Mouse somatosensory cortex; retrograde fluorobead tracing from L1 vs L6 application sites; quantitative laminar-source-pattern comparison",
  "claim_text": "In mouse somatosensory cortex, the laminar profile of long-range cortical input to S1 is statistically different when retrograde fluorobeads are placed in deep layers (centered on L6) versus on the cortical surface (L1), arguing that L1- and L6-targeting long-range inputs originate from distinguishable source populations rather than from a single overlapping pool.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1093/cercor/bhad371",
    "claim": "In mouse somatosensory cortex, the laminar profile of long-range cortical input to S1 is statistically different when retrograde fluorobeads are placed in deep layers (centered on L6) versus on the cortical surface (L1), arguing that L1- and L6-targeting long-range inputs originate from distinguishable source populations rather than from a single overlapping pool.",
    "cite_key": "Ledderose2023",
    "evidence": "Retrograde fluorobead tracing in mouse S1 with comparison of laminar input profiles between surface (L1) and deep (L6) injection sites; statistical testing.",
    "effect_size": "Laminar pattern of long-range S1 input differs significantly between L6-injected and surface (L1)-injected conditions (Supplementary Table 1a, c).",
    "text_access": "fulltext",
    "study_system": "Mouse somatosensory cortex; retrograde fluorobead tracing from L1 vs L6 application sites; quantitative laminar-source-pattern comparison",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "the laminar pattern of long-range input to S1 was statistically, significantly different from that observed with fb application on the cortical surface",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "the laminar pattern of long-range input to S1 was statistically, significantly different from that observed with fb application on the cortical surface ( Supplementary Table 1a and c )."
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Laminar pattern of long-range S1 input differs significantly between L6-injected and surface (L1)-injected conditions (Supplementary Table 1a, c).",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-189d92c83cf0"
  ],
  "source_span": "the laminar pattern of long-range input to S1 was statistically, significantly different from that observed with fb application on the cortical surface",
  "study_system": "Mouse somatosensory cortex; retrograde fluorobead tracing from L1 vs L6 application sites; quantitative laminar-source-pattern comparison",
  "evidence_refs": [
    {
      "ref": "paper:paper-189d92c83cf0"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Retrograde fluorobead tracing in mouse S1 with comparison of laminar input profiles between surface (L1) and deep (L6) injection sites; statistical testing.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}