In mouse somatosensory cortex, the laminar profile of long-range cortical input…

In mouse somatosensory cortex, the laminar profile of long-range cortical input to S1 is statistically different when retrograde fluorobeads are placed in deep layers (centered on L6) versus on the cortical surface (L1), arguing that L1- and L6-targeting long-range inputs originate from distinguishable source populations rather than from a single overlapping pool.

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  "n": 0,
  "doi": "10.1093/cercor/bhad371",
  "claim": "In mouse somatosensory cortex, the laminar profile of long-range cortical input to S1 is statistically different when retrograde fluorobeads are placed in deep layers (centered on L6) versus on the cortical surface (L1), arguing that L1- and L6-targeting long-range inputs originate from distinguishable source populations rather than from a single overlapping pool.",
  "cite_key": "Ledderose2023",
  "evidence": "Retrograde fluorobead tracing in mouse S1 with comparison of laminar input profiles between surface (L1) and deep (L6) injection sites; statistical testing.",
  "effect_size": "Laminar pattern of long-range S1 input differs significantly between L6-injected and surface (L1)-injected conditions (Supplementary Table 1a, c).",
  "text_access": "fulltext",
  "study_system": "Mouse somatosensory cortex; retrograde fluorobead tracing from L1 vs L6 application sites; quantitative laminar-source-pattern comparison",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "the laminar pattern of long-range input to S1 was statistically, significantly different from that observed with fb application on the cortical surface",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "the laminar pattern of long-range input to S1 was statistically, significantly different from that observed with fb application on the cortical surface ( Supplementary Table 1a and c )."
}

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