Version history

{
  "scope": "Mouse V1 (visual cortex); layer L5",
  "claim_text": "Unsupervised representation learning on >30,000 dendritic skeletons from MICrONS V1/AL/RL shows excitatory neuron morphology forms a continuum varying along three axes (soma depth, total apical, total basal length).",
  "raw_fields": {
    "n": 30000,
    "doi": "10.1038/s41467-025-58763-w",
    "claim": "Unsupervised representation learning on >30,000 dendritic skeletons from MICrONS V1/AL/RL shows excitatory neuron morphology forms a continuum varying along three axes (soma depth, total apical, total basal length).",
    "cite_key": "Weis2025",
    "evidence": "Low-dimensional embedding (bar codes) of >30,000 reconstructed dendritic skeletons from MICrONS volume.",
    "effect_size": ">30,000 neurons",
    "text_access": "fulltext",
    "study_system": "Mouse V1 (visual cortex); layer L5",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Our analysis suggests that excitatory neurons’ morphologies form a continuum, with notable exceptions such as layer 5 thick-tufted cells, and vary with respect to three major axes: soma depth, total apical, and total basal skeletal length.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "We apply this approach to a large-scale anatomical datasetto obtain low-dimensional vector embeddings (\"bar codes”) of more than 30,000 neurons in mouse visual areas V1, AL, and RL."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json",
  "effect_size": ">30,000 neurons",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-4be2ac5ab52e"
  ],
  "source_span": "Our analysis suggests that excitatory neurons’ morphologies form a continuum, with notable exceptions such as layer 5 thick-tufted cells, and vary with respect to three major axes: soma depth, total apical, and total basal skeletal length.",
  "study_system": "Mouse V1 (visual cortex); layer L5",
  "evidence_refs": [
    {
      "ref": "paper:paper-4be2ac5ab52e"
    }
  ],
  "section_title": "6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Low-dimensional embedding (bar codes) of >30,000 reconstructed dendritic skeletons from MICrONS volume.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-06-connectomic-micons",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}