Details

scope
Mouse V1 (visual cortex); layer L5
claim_text
Unsupervised representation learning on >30,000 dendritic skeletons from MICrONS V1/AL/RL shows excitatory neuron morphology forms a continuum varying along three axes (soma depth, total apical, total basal length).
section_id
section_06
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
effect_size
>30,000 neurons
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-06-connectomic-micons
source_kind
review_finding
source_path
evidence/section_06_evidence_package.json
source_span
Our analysis suggests that excitatory neurons’ morphologies form a continuum, with notable exceptions such as layer 5 thick-tufted cells, and vary with respect to three major axes: soma depth, total apical, and total basal skeletal length.
study_system
Mouse V1 (visual cortex); layer L5
section_title
6. Connectomic resolution — MICrONS mouse V1/HVA millimetre-scale EM volume; pyramidal-pyramidal wiring statistics derived from it; reconciliation with paired-recording estimates
evidence_summary
Low-dimensional embedding (bar codes) of >30,000 reconstructed dendritic skeletons from MICrONS volume.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-06-connectomic-micons
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_06_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": 30000,
  "doi": "10.1038/s41467-025-58763-w",
  "claim": "Unsupervised representation learning on >30,000 dendritic skeletons from MICrONS V1/AL/RL shows excitatory neuron morphology forms a continuum varying along three axes (soma depth, total apical, total basal length).",
  "cite_key": "Weis2025",
  "evidence": "Low-dimensional embedding (bar codes) of >30,000 reconstructed dendritic skeletons from MICrONS volume.",
  "effect_size": ">30,000 neurons",
  "text_access": "fulltext",
  "study_system": "Mouse V1 (visual cortex); layer L5",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Our analysis suggests that excitatory neurons’ morphologies form a continuum, with notable exceptions such as layer 5 thick-tufted cells, and vary with respect to three major axes: soma depth, total apical, and total basal skeletal length.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "We apply this approach to a large-scale anatomical datasetto obtain low-dimensional vector embeddings (\"bar codes”) of more than 30,000 neurons in mouse visual areas V1, AL, and RL."
}
source_refs
[
  "paper:paper-4be2ac5ab52e"
]
evidence_refs
[
  {
    "ref": "paper:paper-4be2ac5ab52e"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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