Version history

{
  "scope": "mouse, V1, NARP-/- transgenic",
  "claim_text": "NARP is required for excitatory drive onto FS PV interneurons and is obligatory for critical period plasticity",
  "raw_fields": {
    "n": 0,
    "doi": "10.1016/j.neuron.2013.05.016",
    "claim": "NARP is required for excitatory drive onto FS PV interneurons and is obligatory for critical period plasticity",
    "evidence": "NARP-/- visual cortex is hyperexcitable and unable to express OD plasticity; enhancement of FS PV IN inhibitory output recovers plasticity",
    "effect_size": "decreased excitatory inputs; absent OD plasticity; recovery with enhanced inhibition",
    "text_access": "abstract_only",
    "study_system": "mouse, V1, NARP-/- transgenic",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "transgenic deletion of NARP decreases the number of excitatory synaptic inputs onto FS (PV) INs and reduces net excitatory synaptic drive",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "enhancement of this output recovers the expression of experience-dependent synaptic plasticity"
  },
  "section_id": "section_08_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json",
  "effect_size": "decreased excitatory inputs; absent OD plasticity; recovery with enhanced inhibition",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-08",
  "source_kind": "review_finding",
  "source_path": "evidence/section_08_evidence_package.json",
  "source_refs": [
    "paper:paper-422871ce3ed0"
  ],
  "source_span": "transgenic deletion of NARP decreases the number of excitatory synaptic inputs onto FS (PV) INs and reduces net excitatory synaptic drive",
  "study_system": "mouse, V1, NARP-/- transgenic",
  "evidence_refs": [
    {
      "ref": "paper:paper-422871ce3ed0"
    }
  ],
  "section_title": "In Vivo Dynamics and Behavioural Correlates",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "NARP-/- visual cortex is hyperexcitable and unable to express OD plasticity; enhancement of FS PV IN inhibitory output recovers plasticity",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-08",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_08_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}