Version history

{
  "scope": "mouse auditory cortex (AC); L2/3 pyramidal → L5B corticocollicular (PT) and corticocallosal (IT); paired patch + retrograde",
  "claim_text": "Paired recordings between mouse auditory L2/3 pyramidal cells and identified L5B corticocollicular (PT) vs corticocallosal (IT) neurons reveal equal connection probability/amplitude but qualitatively different short-term plasticity: L2/3→corticocollicular synapses do not depress while L2/3→corticocallosal synapses depress substantially.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.0836-14.2015",
    "claim": "Paired recordings between mouse auditory L2/3 pyramidal cells and identified L5B corticocollicular (PT) vs corticocallosal (IT) neurons reveal equal connection probability/amplitude but qualitatively different short-term plasticity: L2/3→corticocollicular synapses do not depress while L2/3→corticocallosal synapses depress substantially.",
    "cite_key": "Joshi2015",
    "evidence": "Paired patch recordings in mouse auditory cortex slices with retrograde labeling of corticocollicular and corticocallosal L5B neurons.",
    "effect_size": "Identical static connectivity (P, amplitude) but opposite short-term plasticity directions across L5B subclass.",
    "text_access": "abstract_only",
    "study_system": "mouse auditory cortex (AC); L2/3 pyramidal → L5B corticocollicular (PT) and corticocallosal (IT); paired patch + retrograde",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "In paired recordings between single L2/3 and labeled L5B neurons, the probabilities of connection, amplitude, latency, rise time, and decay time constant of the unitary EPSC were not different for L2/3→corticocollicular and L2/3→corticocallosal connections. However, short trains of unitary EPSCs showed no synaptic depression in L2/3→corticocollicular connections, but substantial depression in L2/3→corticocallosal connections.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "Identical static connectivity (P, amplitude) but opposite short-term plasticity directions across L5B subclass.",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-1434a55a9a22"
  ],
  "source_span": "In paired recordings between single L2/3 and labeled L5B neurons, the probabilities of connection, amplitude, latency, rise time, and decay time constant of the unitary EPSC were not different for L2/3→corticocollicular and L2/3→corticocallosal connections. However, short trains of unitary EPSCs showed no synaptic depression in L2/3→corticocollicular connections, but substantial depression in L2/3→corticocallosal co...",
  "study_system": "mouse auditory cortex (AC); L2/3 pyramidal → L5B corticocollicular (PT) and corticocallosal (IT); paired patch + retrograde",
  "evidence_refs": [
    {
      "ref": "paper:paper-1434a55a9a22"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Paired patch recordings in mouse auditory cortex slices with retrograde labeling of corticocollicular and corticocallosal L5B neurons.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}