Details

scope
Elife
claim_text
Here, we identify and resolve a fundamental inconsistency between striatal reinforcement learning models and known SPN synaptic plasticity rules.
section_id
section_04
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
effect_size
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-04
source_kind
review_finding
source_path
evidence/section_04_evidence_package.json
source_span
We show that this pathological behavior is reversed if, after action selection, opponent dSPNs and iSPNs receive correlated efferent input encoding the animal’s selected action.
study_system
Elife
section_title
Striatal Output Pathways: Direct, Indirect, and Beyond
evidence_summary
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-04
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_04_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": 0,
  "doi": "10.7554/elife.101747",
  "claim": "Here, we identify and resolve a fundamental inconsistency between striatal reinforcement learning models and known SPN synaptic plasticity rules.",
  "cite_key": "Lindsey2025",
  "evidence": "",
  "effect_size": "",
  "text_access": "fulltext",
  "study_system": "Elife",
  "source_cluster_id": "cluster_04",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We show that this pathological behavior is reversed if, after action selection, opponent dSPNs and iSPNs receive correlated efferent input encoding the animal’s selected action.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "While we illustrated this in a task with sequential trials for visualization purposes, this non-interference enables learning based on delayed reward and efferent feedback from past actions even as the selection of subsequent actions unfolds."
}
source_refs
[
  "paper:paper-64428af7e294"
]
evidence_refs
[
  {
    "ref": "paper:paper-64428af7e294"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

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