Version history

{
  "scope": "mouse V1 in vivo + cited literature",
  "claim_text": "Three non-overlapping cortical interneuron populations — PV, SOM and VIP — collectively account for ~85% of neocortical inhibitory neurons, with VIP cells dispensing local disinhibition through a network motif that is partially constrained by their relatively few but specific local pyramidal-cell drivers.",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.neuron.2016.02.037",
    "claim": "Three non-overlapping cortical interneuron populations — PV, SOM and VIP — collectively account for ~85% of neocortical inhibitory neurons, with VIP cells dispensing local disinhibition through a network motif that is partially constrained by their relatively few but specific local pyramidal-cell drivers.",
    "title": null,
    "cite_key": "Karnani2016a",
    "evidence": "in vivo two-photon Ca2+ imaging in mouse V1 with Cre-driven labeling of PV/SOM/VIP",
    "effect_size": "PV+SOM+VIP ≈ 85% of cortical INs",
    "text_access": "fulltext",
    "study_system": "mouse V1 in vivo + cited literature",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 44,
    "claim_source_sentence": "PVs, together with somatostatin expressing cells (SOMs) and vasoactive intestinal peptide expressing cells (VIPs) form three non-overlapping populations that account for ~85% of neocortical INs (Rudy et al., 2011), and have partially dissociable roles in neural computations.",
    "replication_evidence_dois": [
      "10.1002/dneu.20853",
      "10.1016/j.neuron.2016.06.033"
    ],
    "effect_size_source_sentence": "PVs, together with somatostatin expressing cells (SOMs) and vasoactive intestinal peptide expressing cells (VIPs) form three non-overlapping populations that account for ~85% of neocortical INs."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "PV+SOM+VIP ≈ 85% of cortical INs",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-d405e5906927"
  ],
  "source_span": "PVs, together with somatostatin expressing cells (SOMs) and vasoactive intestinal peptide expressing cells (VIPs) form three non-overlapping populations that account for ~85% of neocortical INs (Rudy et al., 2011), and have partially dissociable roles in neural computations.",
  "study_system": "mouse V1 in vivo + cited literature",
  "evidence_refs": [
    {
      "ref": "paper:paper-d405e5906927"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "in vivo two-photon Ca2+ imaging in mouse V1 with Cre-driven labeling of PV/SOM/VIP",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}