- raw_fields
{
"n": 0,
"doi": "10.1016/j.bbr.2013.04.018",
"claim": "Targeted optogenetic activation of D1 vs D2-receptor-expressing striatal projection neurons elicits opposing motor effects, supporting the canonical direct/indirect pathway model in freely behaving mice.",
"cite_key": "Lenz2013",
"evidence": "Review summarizing ChR2 manipulations in D1-Cre and A2A-Cre mice (e.g., Kravitz 2010 and follow-ups).",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mouse, freely behaving",
"source_cluster_id": "cluster_10",
"replication_status": "independently_replicated",
"claim_source_sentence": "Recent breakthroughs in optogenetic technologies to alter neuronal firing and function with light, combined with cell type-specific transgenic animal lines, has led to important insights into the function of distinct neuronal cell subtypes and afferent connections in the heterogeneously complex striatum.",
"replication_evidence_dois": [
"10.1016/j.expneurol.2016.09.009",
"10.1523/jneurosci.1278-13.2013"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-74401b6c3fd2"
]
- source_span
Recent breakthroughs in optogenetic technologies to alter neuronal firing and function with light, combined with cell type-specific transgenic animal lines, has led to important insights into the function of distinct neuronal cell subtypes and afferent connections in the heterogeneously complex striatum.
- evidence_refs
[
{
"ref": "paper:paper-74401b6c3fd2"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}