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- Live5/17/2026, 4:35:28 PM
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{ "scope": "Mouse S1; large-scale array-tomography (~0.17 mm³ volume); EM cross-validation", "claim_text": "Quantitative array tomography of a ~1 × 0.83 × 0.21 mm³ volume of mouse S1 enables synapse-level mapping of thalamocortical inputs onto whole L5 pyramidal cells, providing a quantitative anatomical method scalable to entire neuron dendritic trees.", "raw_fields": { "n": 0, "doi": "10.3389/fncir.2013.00177", "claim": "Quantitative array tomography of a ~1 × 0.83 × 0.21 mm³ volume of mouse S1 enables synapse-level mapping of thalamocortical inputs onto whole L5 pyramidal cells, providing a quantitative anatomical method scalable to entire neuron dendritic trees.", "cite_key": "Rah2013", "evidence": "Large-scale array tomography volume reconstruction in mouse S1 with quantitative thalamocortical-synapse mapping onto L5 pyramidal neurons; parallel EM validation in L4.", "effect_size": "Reconstructed volume: ~0.17 mm³ (1 × 0.83 × 0.21 mm).", "text_access": "abstract_only", "study_system": "Mouse S1; large-scale array-tomography (~0.17 mm³ volume); EM cross-validation", "argument_role": "supporting", "replication_status": "single_study", "claim_source_sentence": "We then use large-scale array tomography (LSAT) to measure TC synapse distribution on L5 pyramidal neurons in a 1.00 × 0.83 × 0.21 mm(3) volume of mouse somatosensory cortex.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "We then use large-scale array tomography (LSAT) to measure TC synapse distribution on L5 pyramidal neurons in a 1.00 × 0.83 × 0.21 mm(3) volume of mouse somatosensory cortex." }, "section_id": "section_04", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json", "effect_size": "Reconstructed volume: ~0.17 mm³ (1 × 0.83 × 0.21 mm).", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar", "source_kind": "review_finding", "source_path": "evidence/section_04_evidence_package.json", "source_refs": [ "paper:a3fcf790-bfc9-4b6d-a52d-f08e1ebfbc00" ], "source_span": "We then use large-scale array tomography (LSAT) to measure TC synapse distribution on L5 pyramidal neurons in a 1.00 × 0.83 × 0.21 mm(3) volume of mouse somatosensory cortex.", "study_system": "Mouse S1; large-scale array-tomography (~0.17 mm³ volume); EM cross-validation", "evidence_refs": [ { "ref": "paper:a3fcf790-bfc9-4b6d-a52d-f08e1ebfbc00" } ], "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Large-scale array tomography volume reconstruction in mouse S1 with quantitative thalamocortical-synapse mapping onto L5 pyramidal neurons; parallel EM validation in L4.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single_study", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }