Quantitative array tomography of a ~1 × 0.83 × 0.21 mm³ volume of mouse S1 enab…

Quantitative array tomography of a ~1 × 0.83 × 0.21 mm³ volume of mouse S1 enables synapse-level mapping of thalamocortical inputs onto whole L5 pyramidal cells, providing a quantitative anatomical method scalable to entire neuron dendritic trees.

{
  "n": 0,
  "doi": "10.3389/fncir.2013.00177",
  "claim": "Quantitative array tomography of a ~1 × 0.83 × 0.21 mm³ volume of mouse S1 enables synapse-level mapping of thalamocortical inputs onto whole L5 pyramidal cells, providing a quantitative anatomical method scalable to entire neuron dendritic trees.",
  "cite_key": "Rah2013",
  "evidence": "Large-scale array tomography volume reconstruction in mouse S1 with quantitative thalamocortical-synapse mapping onto L5 pyramidal neurons; parallel EM validation in L4.",
  "effect_size": "Reconstructed volume: ~0.17 mm³ (1 × 0.83 × 0.21 mm).",
  "text_access": "abstract_only",
  "study_system": "Mouse S1; large-scale array-tomography (~0.17 mm³ volume); EM cross-validation",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "We then use large-scale array tomography (LSAT) to measure TC synapse distribution on L5 pyramidal neurons in a 1.00 × 0.83 × 0.21 mm(3) volume of mouse somatosensory cortex.",
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  "effect_size_source_sentence": "We then use large-scale array tomography (LSAT) to measure TC synapse distribution on L5 pyramidal neurons in a 1.00 × 0.83 × 0.21 mm(3) volume of mouse somatosensory cortex."
}

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