Details

scope
mouse cortex and subcortical structures, multiple Cre driver lines × Ai14 reporter
claim_text
Cre driver mouse lines using the Cre/loxP binary system enable systematic, brain-wide anatomical labeling of layer- and projection-defined pyramidal cell populations.
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
One of the most widely used approaches is the Cre/loxP binary system, in which the Cre recombinase transgene activates a reporter gene through recombination at loxP sites.
study_system
mouse cortex and subcortical structures, multiple Cre driver lines × Ai14 reporter
section_title
2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)
evidence_summary
Whole-brain anatomical characterization of expression patterns in a panel of Cre driver mouse lines crossed to Ai14 reporter.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.3389/fncir.2014.00076",
  "claim": "Cre driver mouse lines using the Cre/loxP binary system enable systematic, brain-wide anatomical labeling of layer- and projection-defined pyramidal cell populations.",
  "cite_key": "Harris2014",
  "evidence": "Whole-brain anatomical characterization of expression patterns in a panel of Cre driver mouse lines crossed to Ai14 reporter.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "mouse cortex and subcortical structures, multiple Cre driver lines × Ai14 reporter",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "One of the most widely used approaches is the Cre/loxP binary system, in which the Cre recombinase transgene activates a reporter gene through recombination at loxP sites.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-94b8f136b9d7"
]
evidence_refs
[
  {
    "ref": "paper:paper-94b8f136b9d7"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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