Version history

{
  "scope": "MPTP-treated nonhuman primates",
  "claim_text": "MPTP-treated primates with parkinsonism show increased basal-ganglia output rates (GPi/SNr hyperactivity) consistent with the indirect-pathway hyperkinesia model",
  "raw_fields": {
    "n": 0,
    "doi": "10.1016/0166-2236(90)90110-v",
    "claim": "MPTP-treated primates with parkinsonism show increased basal-ganglia output rates (GPi/SNr hyperactivity) consistent with the indirect-pathway hyperkinesia model",
    "cite_key": "DeLong1990",
    "evidence": "Single-unit recording in MPTP primates linking circuit dysfunction to clinical motor signs",
    "effect_size": "",
    "text_access": "abstract_only",
    "study_system": "MPTP-treated nonhuman primates",
    "source_cluster_id": "cluster_04",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Both extremes of this movement disorder spectrum can be accounted for by postulating specific disturbances within the basal ganglia-thalamocortical 'motor' circuit.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.23-05-01916.2003",
      "10.1016/0166-2236(89)90074-x"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json",
  "effect_size": "",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-05",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-d7b8b0eb6812"
  ],
  "source_span": "Both extremes of this movement disorder spectrum can be accounted for by postulating specific disturbances within the basal ganglia-thalamocortical 'motor' circuit.",
  "study_system": "MPTP-treated nonhuman primates",
  "evidence_refs": [
    {
      "ref": "paper:paper-d7b8b0eb6812"
    }
  ],
  "section_title": "Pallidal Organization and the Disinhibition Principle",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Single-unit recording in MPTP primates linking circuit dysfunction to clinical motor signs",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-05",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}