In mouse V1, a substantial fraction of corticocortical feedback synapses contac…

Details

scope: mouse V1 pyramidal apical dendrites; LM→V1 feedback
claim_text: In mouse V1, a substantial fraction of corticocortical feedback synapses contact pyramidal-cell apical dendrites in layer 1, where they cannot influence the soma by passive propagation alone.
section_id: section_04
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
effect_size: apical-tuft localization required for feedback impact
review_repo: ComputationalReviewRecurrence
section_ref: wiki_page:computationalreviewrecurrence-04-translaminar
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: A substantial proportion of feedback inputs innervate pyramidal cell apical dendrites in layer 1 (refs.), in which inputs are too distant to effectively influence the soma passively.
study_system: mouse V1 pyramidal apical dendrites; LM→V1 feedback
section_title: 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
evidence_summary: Long-range all-optical connectivity mapping between LM and V1 with two-photon optogenetics and L1 dendritic calcium imaging.
review_bundle_ref: analysis_bundle:ab-d9c479db9be9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d9c479db9be9
source_artifact_ref: wiki_page:computationalreviewrecurrence-04-translaminar
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
commit_sha: 79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1038/s41586-023-06007-6",
  "claim": "In mouse V1, a substantial fraction of corticocortical feedback synapses contact pyramidal-cell apical dendrites in layer 1, where they cannot influence the soma by passive propagation alone.",
  "cite_key": "Fisek2023",
  "evidence": "Long-range all-optical connectivity mapping between LM and V1 with two-photon optogenetics and L1 dendritic calcium imaging.",
  "effect_size": "apical-tuft localization required for feedback impact",
  "text_access": "fulltext",
  "study_system": "mouse V1 pyramidal apical dendrites; LM→V1 feedback",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "A substantial proportion of feedback inputs innervate pyramidal cell apical dendrites in layer 1 (refs.), in which inputs are too distant to effectively influence the soma passively.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-95604f6d0bfb"
]

evidence_refs

[
  {
    "ref": "paper:paper-95604f6d0bfb"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

In mouse V1, a substantial fraction of corticocortical feedback synapses contac…

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Replication

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