Details

scope
mouse somatosensory barrel cortex, in vitro
claim_text
Thalamocortical stimulation evokes action potentials in ~60% of inhibitory interneurons but less than 5% of excitatory neurons; inhibitory neurons that fire receive 5-fold larger TC inputs compared with non-firing neurons
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
60% of inhibitory vs <5% of excitatory neurons fired; 5-fold larger TC input to firing inhibitory neurons
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse somatosensory barrel cortex, in vitro
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Cell-attached and whole-cell recordings in layers IV and V of mouse somatosensory barrel cortex in vitro
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
independently replicated
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.21-08-02699.2001",
  "claim": "Thalamocortical stimulation evokes action potentials in ~60% of inhibitory interneurons but less than 5% of excitatory neurons; inhibitory neurons that fire receive 5-fold larger TC inputs compared with non-firing neurons",
  "evidence": "Cell-attached and whole-cell recordings in layers IV and V of mouse somatosensory barrel cortex in vitro",
  "effect_size": "60% of inhibitory vs <5% of excitatory neurons fired; 5-fold larger TC input to firing inhibitory neurons",
  "text_access": "abstract_only",
  "study_system": "mouse somatosensory barrel cortex, in vitro",
  "replication_status": "independently replicated",
  "claim_source_sentence": "Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons.",
  "replication_evidence_dois": [
    "10.1523/jneurosci.4727-04.2006",
    "10.1016/j.neuron.2009.12.025"
  ],
  "effect_size_source_sentence": "Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons."
}
source_refs
[
  "paper:paper-3eb6456daece"
]
source_span
Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons.
evidence_refs
[
  {
    "ref": "paper:paper-3eb6456daece"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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