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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse somatosensory barrel cortex, in vitro", "claim_text": "Thalamocortical stimulation evokes action potentials in ~60% of inhibitory interneurons but less than 5% of excitatory neurons; inhibitory neurons that fire receive 5-fold larger TC inputs compared with non-firing neurons", "raw_fields": { "n": 0, "doi": "10.1523/jneurosci.21-08-02699.2001", "claim": "Thalamocortical stimulation evokes action potentials in ~60% of inhibitory interneurons but less than 5% of excitatory neurons; inhibitory neurons that fire receive 5-fold larger TC inputs compared with non-firing neurons", "evidence": "Cell-attached and whole-cell recordings in layers IV and V of mouse somatosensory barrel cortex in vitro", "effect_size": "60% of inhibitory vs <5% of excitatory neurons fired; 5-fold larger TC input to firing inhibitory neurons", "text_access": "abstract_only", "study_system": "mouse somatosensory barrel cortex, in vitro", "replication_status": "independently replicated", "claim_source_sentence": "Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons.", "replication_evidence_dois": [ "10.1523/jneurosci.4727-04.2006", "10.1016/j.neuron.2009.12.025" ], "effect_size_source_sentence": "Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons." }, "section_id": "section_07_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "effect_size": "60% of inhibitory vs <5% of excitatory neurons fired; 5-fold larger TC input to firing inhibitory neurons", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-07", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-3eb6456daece" ], "source_span": "Thalamocortical stimulation evoked action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons. The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons.", "study_system": "mouse somatosensory barrel cortex, in vitro", "evidence_refs": [ { "ref": "paper:paper-3eb6456daece" } ], "section_title": "Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Cell-attached and whole-cell recordings in layers IV and V of mouse somatosensory barrel cortex in vitro", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "independently replicated", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-07", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }