Details
- scope
- Mouse, ACA→VISp and ORB→VISp feedback projections; two-photon imaging + chemogenetics
- claim_text
- Anterior cingulate and orbitofrontal feedback projections to mouse V1 have dissociable functional roles: ACA input enhances visual encoding and scales with arousal, while ORB input reduces high-contrast visual encoding.
- section_id
- section_08
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- effect_size
- ACA carries stronger visual-stimulus information than ORB; opposite-sign effects on high-contrast visual encoding (qualitative).
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- ACA input enhanced visual encoding in VISp neurons and scaled with behavioral arousal, whereas ORB input shaped behavior-related modulation but reduced high-contrast visual encoding.
- study_system
- Mouse, ACA→VISp and ORB→VISp feedback projections; two-photon imaging + chemogenetics
- section_title
- 8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
- evidence_summary
- Axonal tracing, two-photon calcium imaging, and chemogenetic manipulations in mice comparing ACA and ORB inputs to VISp.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single-study
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": null, "doi": "10.1016/j.neuron.2025.10.037", "claim": "Anterior cingulate and orbitofrontal feedback projections to mouse V1 have dissociable functional roles: ACA input enhances visual encoding and scales with arousal, while ORB input reduces high-contrast visual encoding.", "cite_key": "AhrlundRichter2026", "evidence": "Axonal tracing, two-photon calcium imaging, and chemogenetic manipulations in mice comparing ACA and ORB inputs to VISp.", "effect_size": "ACA carries stronger visual-stimulus information than ORB; opposite-sign effects on high-contrast visual encoding (qualitative).", "text_access": "abstract_only", "study_system": "Mouse, ACA→VISp and ORB→VISp feedback projections; two-photon imaging + chemogenetics", "argument_role": "supporting", "replication_status": "single-study", "claim_source_sentence": "ACA input enhanced visual encoding in VISp neurons and scaled with behavioral arousal, whereas ORB input shaped behavior-related modulation but reduced high-contrast visual encoding.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "We found that ACA axons conveyed stronger visual-stimulus information than ORB axons, though both conveyed non-visual, behavior-related information." }- source_refs
[ "paper:paper-8edfacb9362d" ]
- evidence_refs
[ { "ref": "paper:paper-8edfacb9362d" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }