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- Live5/17/2026, 4:35:28 PM
1715635ef275Content snapshot
{ "scope": "Mouse cortex + thalamus tracer atlas (Cre-driver, brain-wide)", "claim_text": "Around one thousand new Cre-driver tracer experiments in the Allen Mouse Brain Connectivity Atlas yielded generalized axon-termination rules for corticocortical, thalamocortical and corticothalamic projections; a model assigning feedforward versus feedback connections placed mouse cortical and thalamic areas in only a shallow hierarchy.", "raw_fields": { "n": 1000, "doi": "10.1038/s41586-019-1716-z", "claim": "Around one thousand new Cre-driver tracer experiments in the Allen Mouse Brain Connectivity Atlas yielded generalized axon-termination rules for corticocortical, thalamocortical and corticothalamic projections; a model assigning feedforward versus feedback connections placed mouse cortical and thalamic areas in only a shallow hierarchy.", "cite_key": "Harris2019", "evidence": "~1,000 Cre-driver tracer experiments, layer- and projection-class-specific; model-assigned hierarchy is shallow in mouse cortex.", "effect_size": "~1,000 tracer experiments; shallow hierarchy of corticothalamic network", "text_access": "fulltext", "study_system": "Mouse cortex + thalamus tracer atlas (Cre-driver, brain-wide)", "argument_role": "supporting", "replication_status": "single-study", "claim_source_sentence": "Through observations of axon termination patterns, we have derived a set of generalized anatomical rules to describe corticocortical, thalamocortical and corticothalamic projections.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "involving around a thousand new tracer experiments in the cortex and its main satellite structure, the thalamus." }, "section_id": "section_15", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "effect_size": "~1,000 tracer experiments; shallow hierarchy of corticothalamic network", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "source_kind": "review_finding", "source_path": "evidence/section_15_evidence_package.json", "source_refs": [ "paper:paper-259a50694faa" ], "source_span": "Through observations of axon termination patterns, we have derived a set of generalized anatomical rules to describe corticocortical, thalamocortical and corticothalamic projections.", "study_system": "Mouse cortex + thalamus tracer atlas (Cre-driver, brain-wide)", "evidence_refs": [ { "ref": "paper:paper-259a50694faa" } ], "section_title": "15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "~1,000 Cre-driver tracer experiments, layer- and projection-class-specific; model-assigned hierarchy is shallow in mouse cortex.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single-study", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }