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- Live5/17/2026, 4:35:28 PM
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{ "scope": "mouse primary auditory cortex, in vitro", "claim_text": "In auditory cortex, the spread of connectivity is comparable for excitatory and inhibitory cell types (85-114 μm Gaussian sigma), but FS unitary synapses are stronger; the comparable spatial patterns can support either lateral inhibition or co-tuning depending on input structure", "raw_fields": { "n": 0, "doi": "10.1523/jneurosci.5158-11.2012", "claim": "In auditory cortex, the spread of connectivity is comparable for excitatory and inhibitory cell types (85-114 μm Gaussian sigma), but FS unitary synapses are stronger; the comparable spatial patterns can support either lateral inhibition or co-tuning depending on input structure", "evidence": "Multiple intracellular recordings in mouse primary auditory cortex slices mapping synaptic connectivity", "effect_size": "Connectivity spread 85-114 μm (Gaussian); FS synapses strongest", "text_access": "abstract_only", "study_system": "mouse primary auditory cortex, in vitro", "replication_status": "single study", "claim_source_sentence": "The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm. With brief stimulus trains, unitary synapses formed by FS interneurons were stronger than other classes of synapses. The comparable spatial patterns of connectivity and relatively strong excitatory-inhibitory interconnectivity are consistent with a theoretical model where either lateral inhibition or co-tuning can predominate, depending on the structure of the input.", "replication_evidence_dois": [], "effect_size_source_sentence": "The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm." }, "section_id": "section_07_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "effect_size": "Connectivity spread 85-114 μm (Gaussian); FS synapses strongest", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-07", "source_kind": "review_finding", "source_path": "evidence/section_07_evidence_package.json", "source_refs": [ "paper:paper-f74b0ebd1b13" ], "source_span": "The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm. With brief stimulus trains, unitary synapses formed by FS interneurons were stronger than other classes of synapses. The comparable spatial patterns of connectivity and relatively strong excitatory-inhibitory interconnectivity are consistent with a theoretical model where either later...", "study_system": "mouse primary auditory cortex, in vitro", "evidence_refs": [ { "ref": "paper:paper-f74b0ebd1b13" } ], "section_title": "Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Multiple intracellular recordings in mouse primary auditory cortex slices mapping synaptic connectivity", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "single study", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-07", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }