Details

scope
mouse primary auditory cortex, in vitro
section_id
section_07_evidence_package
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
effect_size
Connectivity spread 85-114 μm (Gaussian); FS synapses strongest
review_repo
ComputationalReviewPV
section_ref
wiki_page:computationalreviewpv-07
source_kind
review_finding
source_path
evidence/section_07_evidence_package.json
study_system
mouse primary auditory cortex, in vitro
section_title
Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward
evidence_summary
Multiple intracellular recordings in mouse primary auditory cortex slices mapping synaptic connectivity
review_bundle_ref
analysis_bundle:ab-e6261c8263e7
replication_status
single study
review_package_ref
analysis_bundle:ab-e6261c8263e7
source_artifact_ref
wiki_page:computationalreviewpv-07
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json
commit_sha
df9fc7e8d455b084152c9d713558dae0013cef21
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (6)
claim_text
In auditory cortex, the spread of connectivity is comparable for excitatory and inhibitory cell types (85-114 μm Gaussian sigma), but FS unitary synapses are stronger; the comparable spatial patterns can support either lateral inhibition or co-tuning depending on input structure
raw_fields
{
  "n": 0,
  "doi": "10.1523/jneurosci.5158-11.2012",
  "claim": "In auditory cortex, the spread of connectivity is comparable for excitatory and inhibitory cell types (85-114 μm Gaussian sigma), but FS unitary synapses are stronger; the comparable spatial patterns can support either lateral inhibition or co-tuning depending on input structure",
  "evidence": "Multiple intracellular recordings in mouse primary auditory cortex slices mapping synaptic connectivity",
  "effect_size": "Connectivity spread 85-114 μm (Gaussian); FS synapses strongest",
  "text_access": "abstract_only",
  "study_system": "mouse primary auditory cortex, in vitro",
  "replication_status": "single study",
  "claim_source_sentence": "The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm. With brief stimulus trains, unitary synapses formed by FS interneurons were stronger than other classes of synapses. The comparable spatial patterns of connectivity and relatively strong excitatory-inhibitory interconnectivity are consistent with a theoretical model where either lateral inhibition or co-tuning can predominate, depending on the structure of the input.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm."
}
source_refs
[
  "paper:paper-f74b0ebd1b13"
]
source_span
The spread of connectivity, parameterized by Gaussian fits to the data, was comparable for all cell types, ranging from 85 to 114 μm. With brief stimulus trains, unitary synapses formed by FS interneurons were stronger than other classes of synapses. The comparable spatial patterns of connectivity and relatively strong excitatory-inhibitory interconnectivity are consistent with a theoretical model where either later...
evidence_refs
[
  {
    "ref": "paper:paper-f74b0ebd1b13"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}

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