Version history

{
  "scope": "mouse hippocampal basket cells, P6 to P25",
  "claim_text": "Hippocampal basket cells undergo marked changes between P6 and P25: action potential duration, propagation time, release period duration, and IPSC decay time constant decrease by 30-60%, converting BCs from slow to fast signaling devices necessary for gamma oscillations.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.2890-08.2008",
    "claim": "Hippocampal basket cells undergo marked changes between P6 and P25: action potential duration, propagation time, release period duration, and IPSC decay time constant decrease by 30-60%, converting BCs from slow to fast signaling devices necessary for gamma oscillations.",
    "evidence": "Computational analysis showed BC networks with young properties generate lower gamma coherence; mature properties with increased connectivity enable highly coherent upper gamma activity.",
    "effect_size": "30-60% decrease in AP duration, propagation time, release period, and IPSC decay time constant between P6-P25",
    "text_access": "abstract_only",
    "study_system": "mouse hippocampal basket cells, P6 to P25",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "During maturation, action potential duration, propagation time, duration of the release period, and decay time constant of IPSCs decreases by ~30-60%. Thus, postnatal development converts BCs from slow into fast signaling devices.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.0105-09.2009"
    ],
    "effect_size_source_sentence": "action potential duration, propagation time, duration of the release period, and decay time constant of IPSCs decreases by ~30-60%."
  },
  "section_id": "section_05_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json",
  "effect_size": "30-60% decrease in AP duration, propagation time, release period, and IPSC decay time constant between P6-P25",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-05",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-7c89812b5c9d"
  ],
  "source_span": "During maturation, action potential duration, propagation time, duration of the release period, and decay time constant of IPSCs decreases by ~30-60%. Thus, postnatal development converts BCs from slow into fast signaling devices.",
  "study_system": "mouse hippocampal basket cells, P6 to P25",
  "evidence_refs": [
    {
      "ref": "paper:paper-7c89812b5c9d"
    }
  ],
  "section_title": "Intrinsic Electrophysiology: The Fast-Spiking Phenotype and Its Variants",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Computational analysis showed BC networks with young properties generate lower gamma coherence; mature properties with increased connectivity enable highly coherent upper gamma activity.",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-05",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_05_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}