Details
- scope
- mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task
- section_id
- section_10
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json
- effect_size
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-10-persistent-activity
- source_kind
- review_finding
- source_path
- evidence/section_10_evidence_package.json
- source_span
- Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus. In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.
- study_system
- mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task
- section_title
- 10. Physiological signature II — persistent activity and attractor dynamics supported by E→E recurrence (delay-period activity in mouse PFC/ALM, working memory, head-direction)
- evidence_summary
- Projection-specific two-photon calcium imaging and optogenetic manipulations show that ACC outputs to the superior colliculus, a key midbrain structure for response selection, principally coordinate specific motor responses.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- single_lab
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-10-persistent-activity
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
- claim_text
Projection-specific two-photon calcium imaging and optogenetic manipulations in mouse anterior cingulate cortex during a visually-guided two-choice task with multiple cue–response mappings show that ACC outputs to superior colliculus principally coordinate motor-response selection — reducing the SC's innate response bias — while a separate ACC→visual-cortex output facilitates sensory processing of visual cues; dissociated motor and sensory channels in non-overlapping ACC projection populations.
- raw_fields
{ "n": 0, "doi": "10.1038/s41467-020-19772-z", "claim": "Projection-specific two-photon calcium imaging and optogenetic manipulations in mouse anterior cingulate cortex during a visually-guided two-choice task with multiple cue–response mappings show that ACC outputs to superior colliculus principally coordinate motor-response selection — reducing the SC's innate response bias — while a separate ACC→visual-cortex output facilitates sensory processing of visual cues; dissociated motor and sensory channels in non-overlapping ACC projection populations.", "cite_key": "Huda2020", "evidence": "Projection-specific two-photon calcium imaging and optogenetic manipulations show that ACC outputs to the superior colliculus, a key midbrain structure for response selection, principally coordinate specific motor responses.", "effect_size": "", "text_access": "fulltext", "study_system": "mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task", "argument_role": "supporting", "replication_status": "single_lab", "claim_source_sentence": "Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus. In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": null }- source_refs
[ "paper:paper-76648660797f" ]
- evidence_refs
[ { "ref": "paper:paper-76648660797f" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }