Version history

{
  "scope": "mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task",
  "claim_text": "Projection-specific two-photon calcium imaging and optogenetic manipulations in mouse anterior cingulate cortex during a visually-guided two-choice task with multiple cue–response mappings show that ACC outputs to superior colliculus principally coordinate motor-response selection — reducing the SC's innate response bias — while a separate ACC→visual-cortex output facilitates sensory processing of visual cues; dissociated motor and sensory channels in non-overlapping ACC projection populations.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41467-020-19772-z",
    "claim": "Projection-specific two-photon calcium imaging and optogenetic manipulations in mouse anterior cingulate cortex during a visually-guided two-choice task with multiple cue–response mappings show that ACC outputs to superior colliculus principally coordinate motor-response selection — reducing the SC's innate response bias — while a separate ACC→visual-cortex output facilitates sensory processing of visual cues; dissociated motor and sensory channels in non-overlapping ACC projection populations.",
    "cite_key": "Huda2020",
    "evidence": "Projection-specific two-photon calcium imaging and optogenetic manipulations show that ACC outputs to the superior colliculus, a key midbrain structure for response selection, principally coordinate specific motor responses.",
    "effect_size": "",
    "text_access": "fulltext",
    "study_system": "mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task",
    "argument_role": "supporting",
    "replication_status": "single_lab",
    "claim_source_sentence": "Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus. In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_10",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json",
  "effect_size": "",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity",
  "source_kind": "review_finding",
  "source_path": "evidence/section_10_evidence_package.json",
  "source_refs": [
    "paper:paper-76648660797f"
  ],
  "source_span": "Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus. In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.",
  "study_system": "mouse anterior cingulate cortex; projection-specific two-photon calcium imaging + optogenetic perturbation of ACC→SC and ACC→V1 outputs during a two-choice visually guided task",
  "evidence_refs": [
    {
      "ref": "paper:paper-76648660797f"
    }
  ],
  "section_title": "10. Physiological signature II — persistent activity and attractor dynamics supported by E→E recurrence (delay-period activity in mouse PFC/ALM, working memory, head-direction)",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Projection-specific two-photon calcium imaging and optogenetic manipulations show that ACC outputs to the superior colliculus, a key midbrain structure for response selection, principally coordinate specific motor responses.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_lab",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-10-persistent-activity",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_10_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}