Details

scope
Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics
claim_text
Cortico-cortical feedback from LM to V1 is non-linearly integrated in apical dendrites of V1 pyramidal cells, with retinotopically-offset feedback being facilitating and aligned feedback being suppressive.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json
effect_size
Retinotopically aligned feedback: suppressive; offset feedback: facilitating; apical-tuft regenerative dendritic events
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-14-predictive-coding
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
We found that visual stimuli could evoke local dendritic calcium transients that were spatially more extensive than single spine events, but not as extensive as global calcium events.
study_system
Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics
section_title
14. Predictive-coding and dynamical-systems accounts — the role of recurrent excitatory feedback in error signalling, state estimation, and reservoir computing, evaluated against mouse data
evidence_summary
Long-range all-optical connectivity mapping + two-photon imaging in mouse V1; two-photon optogenetic activation of LM neurons drove branch-specific apical-dendrite Ca²⁺ signals in V1.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-14-predictive-coding
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41586-023-06007-6",
  "claim": "Cortico-cortical feedback from LM to V1 is non-linearly integrated in apical dendrites of V1 pyramidal cells, with retinotopically-offset feedback being facilitating and aligned feedback being suppressive.",
  "cite_key": "Fisek2023",
  "evidence": "Long-range all-optical connectivity mapping + two-photon imaging in mouse V1; two-photon optogenetic activation of LM neurons drove branch-specific apical-dendrite Ca²⁺ signals in V1.",
  "effect_size": "Retinotopically aligned feedback: suppressive; offset feedback: facilitating; apical-tuft regenerative dendritic events",
  "text_access": "fulltext",
  "study_system": "Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "We found that visual stimuli could evoke local dendritic calcium transients that were spatially more extensive than single spine events, but not as extensive as global calcium events.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "By contrast, when the source is offset from the target in visual space, feedback is relatively facilitating."
}
source_refs
[
  "paper:paper-95604f6d0bfb"
]
evidence_refs
[
  {
    "ref": "paper:paper-95604f6d0bfb"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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