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- Live5/17/2026, 4:35:28 PM
93b89a335b0fContent snapshot
{ "scope": "Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics", "claim_text": "Cortico-cortical feedback from LM to V1 is non-linearly integrated in apical dendrites of V1 pyramidal cells, with retinotopically-offset feedback being facilitating and aligned feedback being suppressive.", "raw_fields": { "n": null, "doi": "10.1038/s41586-023-06007-6", "claim": "Cortico-cortical feedback from LM to V1 is non-linearly integrated in apical dendrites of V1 pyramidal cells, with retinotopically-offset feedback being facilitating and aligned feedback being suppressive.", "cite_key": "Fisek2023", "evidence": "Long-range all-optical connectivity mapping + two-photon imaging in mouse V1; two-photon optogenetic activation of LM neurons drove branch-specific apical-dendrite Ca²⁺ signals in V1.", "effect_size": "Retinotopically aligned feedback: suppressive; offset feedback: facilitating; apical-tuft regenerative dendritic events", "text_access": "fulltext", "study_system": "Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "We found that visual stimuli could evoke local dendritic calcium transients that were spatially more extensive than single spine events, but not as extensive as global calcium events.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "By contrast, when the source is offset from the target in visual space, feedback is relatively facilitating." }, "section_id": "section_14", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json", "effect_size": "Retinotopically aligned feedback: suppressive; offset feedback: facilitating; apical-tuft regenerative dendritic events", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding", "source_kind": "review_finding", "source_path": "evidence/section_14_evidence_package.json", "source_refs": [ "paper:paper-95604f6d0bfb" ], "source_span": "We found that visual stimuli could evoke local dendritic calcium transients that were spatially more extensive than single spine events, but not as extensive as global calcium events.", "study_system": "Mouse V1 + LM; all-optical mapping, two-photon imaging, holographic optogenetics", "evidence_refs": [ { "ref": "paper:paper-95604f6d0bfb" } ], "section_title": "14. Predictive-coding and dynamical-systems accounts — the role of recurrent excitatory feedback in error signalling, state estimation, and reservoir computing, evaluated against mouse data", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Long-range all-optical connectivity mapping + two-photon imaging in mouse V1; two-photon optogenetic activation of LM neurons drove branch-specific apical-dendrite Ca²⁺ signals in V1.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }