- claim_text
Pathway-specific optogenetic activation of caudate-tail terminals in SNr inhibits SNr neurons preferentially encoding good-object values, prolongs SC visual-saccadic neuron excitation and induces contralateral saccades — directly demonstrating a serial CDt→SNr→SC inhibitory disinhibition pathway driving value-based gaze in primate.
- raw_fields
{
"n": 0,
"doi": "10.1038/s41467-020-15802-y",
"claim": "Pathway-specific optogenetic activation of caudate-tail terminals in SNr inhibits SNr neurons preferentially encoding good-object values, prolongs SC visual-saccadic neuron excitation and induces contralateral saccades — directly demonstrating a serial CDt→SNr→SC inhibitory disinhibition pathway driving value-based gaze in primate.",
"cite_key": "Amita2020",
"evidence": "Pathway-selective optogenetic activation in macaque CDt-derived SNr terminals with SNr/SC recordings and behavior.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "macaque (viral optogenetics)",
"source_cluster_id": "cluster_02",
"replication_status": "replicated",
"claim_source_sentence": "Selective optical activation of CDt-derived terminals in the substantia nigra pars reticulata (SNr) inhibits SNr neurons.",
"replication_evidence_dois": [
"10.1152/jn.00674.2014",
"10.1111/ejn.13936"
],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-4e82d65b2263"
]
- evidence_refs
[
{
"ref": "paper:paper-4e82d65b2263"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}