Version history

{
  "scope": "macaque (viral optogenetics)",
  "claim_text": "Pathway-specific optogenetic activation of caudate-tail terminals in SNr inhibits SNr neurons preferentially encoding good-object values, prolongs SC visual-saccadic neuron excitation and induces contralateral saccades — directly demonstrating a serial CDt→SNr→SC inhibitory disinhibition pathway driving value-based gaze in primate.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41467-020-15802-y",
    "claim": "Pathway-specific optogenetic activation of caudate-tail terminals in SNr inhibits SNr neurons preferentially encoding good-object values, prolongs SC visual-saccadic neuron excitation and induces contralateral saccades — directly demonstrating a serial CDt→SNr→SC inhibitory disinhibition pathway driving value-based gaze in primate.",
    "cite_key": "Amita2020",
    "evidence": "Pathway-selective optogenetic activation in macaque CDt-derived SNr terminals with SNr/SC recordings and behavior.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "macaque (viral optogenetics)",
    "source_cluster_id": "cluster_02",
    "replication_status": "replicated",
    "claim_source_sentence": "Selective optical activation of CDt-derived terminals in the substantia nigra pars reticulata (SNr) inhibits SNr neurons.",
    "replication_evidence_dois": [
      "10.1152/jn.00674.2014",
      "10.1111/ejn.13936"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_02",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-02",
  "source_kind": "review_finding",
  "source_path": "evidence/section_02_evidence_package.json",
  "source_refs": [
    "paper:paper-4e82d65b2263"
  ],
  "source_span": "Selective optical activation of CDt-derived terminals in the substantia nigra pars reticulata (SNr) inhibits SNr neurons.",
  "study_system": "macaque (viral optogenetics)",
  "evidence_refs": [
    {
      "ref": "paper:paper-4e82d65b2263"
    }
  ],
  "section_title": "Classical Anatomy of the Triple Descending Projection",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Pathway-selective optogenetic activation in macaque CDt-derived SNr terminals with SNr/SC recordings and behavior.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-02",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_02_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}