Version history

{
  "scope": "zebra finch (songbird) Area X (basal ganglia); lentivirus-mediated FoxP2 RNAi",
  "claim_text": "Lentivirus-mediated knockdown of FoxP2 in zebra-finch song-learning nucleus Area X causes incomplete and inaccurate imitation of tutor song with abnormally variable acoustic structure and syllable duration, paralleling features of human FOXP2-related developmental verbal dyspraxia.",
  "raw_fields": {
    "n": 2,
    "doi": "10.1371/journal.pbio.0050321",
    "claim": "Lentivirus-mediated knockdown of FoxP2 in zebra-finch song-learning nucleus Area X causes incomplete and inaccurate imitation of tutor song with abnormally variable acoustic structure and syllable duration, paralleling features of human FOXP2-related developmental verbal dyspraxia.",
    "cite_key": "Haesler2007",
    "evidence": "Lentiviral RNAi against FoxP2 was injected into Area X (a basal-ganglia nucleus required for song learning) before zebra finches began song learning; tutor-imitation accuracy and syllable variability were quantified in adulthood.",
    "effect_size": "adult song syllables abnormally variable in acoustic structure and duration",
    "text_access": "fulltext",
    "study_system": "zebra finch (songbird) Area X (basal ganglia); lentivirus-mediated FoxP2 RNAi",
    "source_cluster_id": "cluster_14",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Knockdown of FoxP2 resulted in an incomplete and inaccurate imitation of tutor song.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "The acoustic structure and the duration of adult song syllables were abnormally variable, similar to word production in children with DVD."
  },
  "section_id": "section_15",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_15_evidence_package.json",
  "effect_size": "adult song syllables abnormally variable in acoustic structure and duration",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-15",
  "source_kind": "review_finding",
  "source_path": "evidence/section_15_evidence_package.json",
  "source_refs": [
    "paper:962eed37-5430-4e42-a2ac-353fbc9e9dfd"
  ],
  "source_span": "Knockdown of FoxP2 resulted in an incomplete and inaccurate imitation of tutor song.",
  "study_system": "zebra finch (songbird) Area X (basal ganglia); lentivirus-mediated FoxP2 RNAi",
  "evidence_refs": [
    {
      "ref": "paper:962eed37-5430-4e42-a2ac-353fbc9e9dfd"
    }
  ],
  "section_title": "Species Differences and Evolutionary Scaling of Loop Architecture",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Lentiviral RNAi against FoxP2 was injected into Area X (a basal-ganglia nucleus required for song learning) before zebra finches began song learning; tutor-imitation accuracy and syllable variability were quantified in adulthood.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-15",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_15_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}