Details
- scope
- Mouse (Cre driver lines, C57BL/6J background); cortex + thalamus
- claim_text
- Cell-class-specific cortico-cortical connections in mouse cortex are organized in a shallow hierarchy in which feedforward vs feedback assignment can be inferred from axon termination patterns across ~1,000 new Allen tracer experiments.
- section_id
- section_08
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- effect_size
- ~1,000 new tracer experiments; hierarchy described as 'shallow'
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- source_kind
- review_finding
- source_path
- evidence/section_08_evidence_package.json
- source_span
- Our results show that cell-class-specific connections are organized in a shallow hierarchy within the mouse corticothalamic network.
- study_system
- Mouse (Cre driver lines, C57BL/6J background); cortex + thalamus
- section_title
- 8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
- evidence_summary
- Allen Mouse Brain Connectivity Atlas expansion with ~1,000 Cre-driver-line tracer injections; FF/FB labels assigned from axon-termination patterns and used to derive hierarchy scores for individual cortical areas and network modules.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-08-cross-areal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
- raw_fields
{ "n": 1000, "doi": "10.1038/s41586-019-1716-z", "claim": "Cell-class-specific cortico-cortical connections in mouse cortex are organized in a shallow hierarchy in which feedforward vs feedback assignment can be inferred from axon termination patterns across ~1,000 new Allen tracer experiments.", "cite_key": "Harris2019", "evidence": "Allen Mouse Brain Connectivity Atlas expansion with ~1,000 Cre-driver-line tracer injections; FF/FB labels assigned from axon-termination patterns and used to derive hierarchy scores for individual cortical areas and network modules.", "effect_size": "~1,000 new tracer experiments; hierarchy described as 'shallow'", "text_access": "abstract_only", "study_system": "Mouse (Cre driver lines, C57BL/6J background); cortex + thalamus", "argument_role": "supporting", "replication_status": "replicated", "claim_source_sentence": "Our results show that cell-class-specific connections are organized in a shallow hierarchy within the mouse corticothalamic network.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [ "10.1016/j.cell.2020.04.007", "10.7554/eLife.59551" ], "effect_size_source_sentence": "Here we describe a major expansion of the Allen Mouse Brain Connectivity Atlas resource, involving around a thousand new tracer experiments in the cortex and its main satellite structure, the thalamus." }- source_refs
[ "paper:paper-259a50694faa" ]
- evidence_refs
[ { "ref": "paper:paper-259a50694faa" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }