Version history

{
  "scope": "mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction",
  "claim_text": "Major cortical projection neuron types exhibit extensive long-range axonal diversity governed by generalizable principles including divergent/convergent projection patterns, regional specificity, and topography, with 11 major types identified from complete single-neuron reconstructions.",
  "raw_fields": {
    "n": 1741,
    "doi": "10.1038/s41586-021-03941-1",
    "claim": "Major cortical projection neuron types exhibit extensive long-range axonal diversity governed by generalizable principles including divergent/convergent projection patterns, regional specificity, and topography, with 11 major types identified from complete single-neuron reconstructions.",
    "cite_key": "Peng2021",
    "evidence": "Complete single-neuron morphological reconstructions of 1,741 neurons from mouse cortex and other brain regions using sparse labeling, whole-brain imaging, and registration pipeline.",
    "effect_size": "1,741 neurons reconstructed; 11 major projection neuron types identified",
    "text_access": "abstract_only",
    "study_system": "mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction",
    "argument_role": "supporting",
    "replication_status": "novel",
    "claim_source_sentence": "This diversity follows a set of generalizable principles that govern long-range axonal projections at different levels, including molecular correspondence, divergent or convergent projection, axon termination pattern, regional specificity, topography, and individual cell variability.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "effect_size": "1,741 neurons reconstructed; 11 major projection neuron types identified",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-aa79acad2563"
  ],
  "source_span": "This diversity follows a set of generalizable principles that govern long-range axonal projections at different levels, including molecular correspondence, divergent or convergent projection, axon termination pattern, regional specificity, topography, and individual cell variability.",
  "study_system": "mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction",
  "evidence_refs": [
    {
      "ref": "paper:paper-aa79acad2563"
    }
  ],
  "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Complete single-neuron morphological reconstructions of 1,741 neurons from mouse cortex and other brain regions using sparse labeling, whole-brain imaging, and registration pipeline.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "novel",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}