Details
- scope
- mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- effect_size
- 1,741 neurons reconstructed; 11 major projection neuron types identified
- review_repo
- ComputationalReviewRecurrence
- section_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- study_system
- mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction
- section_title
- 5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay
- evidence_summary
- Complete single-neuron morphological reconstructions of 1,741 neurons from mouse cortex and other brain regions using sparse labeling, whole-brain imaging, and registration pipeline.
- review_bundle_ref
- analysis_bundle:ab-d9c479db9be9
- replication_status
- novel
- review_package_ref
- analysis_bundle:ab-d9c479db9be9
- source_artifact_ref
- wiki_page:computationalreviewrecurrence-05-horizontal
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json
- commit_sha
- 79ce062d54a924ce05953ec90aa9d26044d2b48f
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
- claim_text
Major cortical projection neuron types exhibit extensive long-range axonal diversity governed by generalizable principles including divergent/convergent projection patterns, regional specificity, and topography, with 11 major types identified from complete single-neuron reconstructions.
- raw_fields
{ "n": 1741, "doi": "10.1038/s41586-021-03941-1", "claim": "Major cortical projection neuron types exhibit extensive long-range axonal diversity governed by generalizable principles including divergent/convergent projection patterns, regional specificity, and topography, with 11 major types identified from complete single-neuron reconstructions.", "cite_key": "Peng2021", "evidence": "Complete single-neuron morphological reconstructions of 1,741 neurons from mouse cortex and other brain regions using sparse labeling, whole-brain imaging, and registration pipeline.", "effect_size": "1,741 neurons reconstructed; 11 major projection neuron types identified", "text_access": "abstract_only", "study_system": "mouse cortex/subcortical regions, sparse labeling + whole-brain imaging + full morphological reconstruction", "argument_role": "supporting", "replication_status": "novel", "claim_source_sentence": "This diversity follows a set of generalizable principles that govern long-range axonal projections at different levels, including molecular correspondence, divergent or convergent projection, axon termination pattern, regional specificity, topography, and individual cell variability.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "We fully reconstructed 1,741 neurons from cortex, claustrum, thalamus, striatum and other brain regions in mice." }- source_refs
[ "paper:paper-aa79acad2563" ]
- source_span
This diversity follows a set of generalizable principles that govern long-range axonal projections at different levels, including molecular correspondence, divergent or convergent projection, axon termination pattern, regional specificity, topography, and individual cell variability.
- evidence_refs
[ { "ref": "paper:paper-aa79acad2563" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }