Version history

{
  "scope": "mouse cortico-thalamic connectivity (Cre-driver tract tracing)",
  "claim_text": "A hierarchical, layer-/cell-class-specific organization of corticocortical, thalamocortical and corticothalamic projections defines feedforward vs feedback positions across mouse cortical and thalamic areas.",
  "raw_fields": {
    "n": 1000,
    "doi": "10.1038/s41586-019-1716-z",
    "claim": "A hierarchical, layer-/cell-class-specific organization of corticocortical, thalamocortical and corticothalamic projections defines feedforward vs feedback positions across mouse cortical and thalamic areas.",
    "cite_key": "Harris2019",
    "evidence": "Roughly one thousand additional Cre-driver tract-tracing experiments resolving thalamus-included hierarchies in the mouse cortex.",
    "effect_size": "~1000 cell-class–specific tracer experiments",
    "text_access": "fulltext",
    "study_system": "mouse cortico-thalamic connectivity (Cre-driver tract tracing)",
    "source_cluster_id": "cluster_05",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "We have built a model to assign connection patterns between areas as either feedforward or feedback, and generated testable predictions of hierarchical positions for individual cortical and thalamic areas and for cortical network modules.",
    "replication_evidence_dois": [
      "10.1038/nature13186",
      "10.1038/nn.4197"
    ],
    "effect_size_source_sentence": "Here we describe a major expansion of the Allen Mouse Brain Connectivity Atlas resource1, involving around a thousand new tracer experiments in the cortex and its main satellite structure, the thalamus."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "effect_size": "~1000 cell-class–specific tracer experiments",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-06",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-259a50694faa"
  ],
  "source_span": "We have built a model to assign connection patterns between areas as either feedforward or feedback, and generated testable predictions of hierarchical positions for individual cortical and thalamic areas and for cortical network modules.",
  "study_system": "mouse cortico-thalamic connectivity (Cre-driver tract tracing)",
  "evidence_refs": [
    {
      "ref": "paper:paper-259a50694faa"
    }
  ],
  "section_title": "Thalamic Feedback: Closing the Loop",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Roughly one thousand additional Cre-driver tract-tracing experiments resolving thalamus-included hierarchies in the mouse cortex.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-06",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}