Version history

{
  "scope": "mouse V1 L2/3 in vivo, 2P calcium + patch-clamp single-cell stimulation",
  "claim_text": "Patch-clamp activation of single L2/3 or L4 pyramidal neurons in mouse V1 produces only sparse single-cell followers (<0.75% of nearby L2/3 cells within ~200 μm) — substantially fewer than canonical-microcircuit pairwise estimates would imply.",
  "raw_fields": {
    "n": 0,
    "doi": "10.3389/fncir.2018.00029",
    "claim": "Patch-clamp activation of single L2/3 or L4 pyramidal neurons in mouse V1 produces only sparse single-cell followers (<0.75% of nearby L2/3 cells within ~200 μm) — substantially fewer than canonical-microcircuit pairwise estimates would imply.",
    "cite_key": "Meyer2018",
    "evidence": "Two-photon calcium imaging in mouse V1 with single-cell patch-clamp stimulation of L2/3 or L4 pyramidal neurons in vivo.",
    "effect_size": "<0.75% reliably activated followers within 200 μm radius",
    "text_access": "abstract_only",
    "study_system": "mouse V1 L2/3 in vivo, 2P calcium + patch-clamp single-cell stimulation",
    "argument_role": "supporting",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Using this approach, we found only a small fraction (<0.75%) of L2/3 cells to be significantly activated within a radius of ~200 μm from a stimulated neighboring L2/3 pyramidal cell. This fraction did not change significantly in the awake vs. the lightly anesthetized state, nor when stimulating L2/3 vs. underlying L4 pyramidal neurons.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Using this approach, we found only a small fraction (<0.75%) of L2/3 cells to be significantly activated within a radius of ~200 μm from a stimulated neighboring L2/3 pyramidal cell."
  },
  "section_id": "section_04",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "effect_size": "<0.75% reliably activated followers within 200 μm radius",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "source_kind": "review_finding",
  "source_path": "evidence/section_04_evidence_package.json",
  "source_refs": [
    "paper:paper-068169bdf0b1"
  ],
  "source_span": "Using this approach, we found only a small fraction (<0.75%) of L2/3 cells to be significantly activated within a radius of ~200 μm from a stimulated neighboring L2/3 pyramidal cell. This fraction did not change significantly in the awake vs. the lightly anesthetized state, nor when stimulating L2/3 vs. underlying L4 pyramidal neurons.",
  "study_system": "mouse V1 L2/3 in vivo, 2P calcium + patch-clamp single-cell stimulation",
  "evidence_refs": [
    {
      "ref": "paper:paper-068169bdf0b1"
    }
  ],
  "section_title": "4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon calcium imaging in mouse V1 with single-cell patch-clamp stimulation of L2/3 or L4 pyramidal neurons in vivo.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-04-translaminar",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}