Version history

{
  "scope": "mouse hippocampus CA1 → subiculum",
  "claim_text": "A subset of CA1 hippocampal VIP+ interneurons (VIP-LRPs) project long-range axons to the subiculum, targeting interneurons in CA1 and both interneurons and pyramidal cells in subiculum; VIP-LRPs are interconnected by gap junctions with sparse spike coupling, decrease activity during theta-run epochs and are more active during quiet wakefulness.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41467-018-07162-5",
    "claim": "A subset of CA1 hippocampal VIP+ interneurons (VIP-LRPs) project long-range axons to the subiculum, targeting interneurons in CA1 and both interneurons and pyramidal cells in subiculum; VIP-LRPs are interconnected by gap junctions with sparse spike coupling, decrease activity during theta-run epochs and are more active during quiet wakefulness.",
    "title": null,
    "cite_key": "Francavilla2018a",
    "evidence": "Anatomical and electrophysiological characterization of VIP+ projection neurons in mouse hippocampus + in vivo recordings.",
    "effect_size": "Gap-junction-coupled subnetwork; sparse electrical spike coupling.",
    "text_access": "abstract_only",
    "study_system": "mouse hippocampus CA1 → subiculum",
    "_source_cluster": "cluster_05_synaptic_connectivity",
    "replication_status": "single-study",
    "_source_cluster_index": 27,
    "claim_source_sentence": "Here, we discover a type of VIP+ neuron whose axon innervates CA1 and also projects to the subiculum (VIP-LRPs). VIP-LRPs show specific molecular properties and target interneurons within the CA1 area but both interneurons and pyramidal cells within subiculum.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "effect_size": "Gap-junction-coupled subnetwork; sparse electrical spike coupling.",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-c5dc6d520729"
  ],
  "source_span": "Here, we discover a type of VIP+ neuron whose axon innervates CA1 and also projects to the subiculum (VIP-LRPs). VIP-LRPs show specific molecular properties and target interneurons within the CA1 area but both interneurons and pyramidal cells within subiculum.",
  "study_system": "mouse hippocampus CA1 → subiculum",
  "evidence_refs": [
    {
      "ref": "paper:paper-c5dc6d520729"
    }
  ],
  "section_title": "Synaptic Properties and Connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Anatomical and electrophysiological characterization of VIP+ projection neurons in mouse hippocampus + in vivo recordings.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}