- claim_text
A subset of CA1 hippocampal VIP+ interneurons (VIP-LRPs) project long-range axons to the subiculum, targeting interneurons in CA1 and both interneurons and pyramidal cells in subiculum; VIP-LRPs are interconnected by gap junctions with sparse spike coupling, decrease activity during theta-run epochs and are more active during quiet wakefulness.
- raw_fields
{
"n": null,
"doi": "10.1038/s41467-018-07162-5",
"claim": "A subset of CA1 hippocampal VIP+ interneurons (VIP-LRPs) project long-range axons to the subiculum, targeting interneurons in CA1 and both interneurons and pyramidal cells in subiculum; VIP-LRPs are interconnected by gap junctions with sparse spike coupling, decrease activity during theta-run epochs and are more active during quiet wakefulness.",
"title": null,
"cite_key": "Francavilla2018a",
"evidence": "Anatomical and electrophysiological characterization of VIP+ projection neurons in mouse hippocampus + in vivo recordings.",
"effect_size": "Gap-junction-coupled subnetwork; sparse electrical spike coupling.",
"text_access": "abstract_only",
"study_system": "mouse hippocampus CA1 → subiculum",
"_source_cluster": "cluster_05_synaptic_connectivity",
"replication_status": "single-study",
"_source_cluster_index": 27,
"claim_source_sentence": "Here, we discover a type of VIP+ neuron whose axon innervates CA1 and also projects to the subiculum (VIP-LRPs). VIP-LRPs show specific molecular properties and target interneurons within the CA1 area but both interneurons and pyramidal cells within subiculum.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-c5dc6d520729"
]
- source_span
Here, we discover a type of VIP+ neuron whose axon innervates CA1 and also projects to the subiculum (VIP-LRPs). VIP-LRPs show specific molecular properties and target interneurons within the CA1 area but both interneurons and pyramidal cells within subiculum.
- evidence_refs
[
{
"ref": "paper:paper-c5dc6d520729"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}